By H.-J. Biersack (auth.), Hans Bender MD, Holger Palmedo MD, Hans-Jürgen Biersack MD, Peter E. Valk MD (eds.)
Clinical reports up to now 10 years have proven that puppy is extra delicate than CT and MRI for the detection of many tumors. in lots of circumstances, notwithstanding, for instance in head and neck tumors, mixture with radiological systems is critical. it can be speculated that puppy will be the 1st examine in a malignant tumor while metastatic unfold is suspected. MRI and CT could then be limited to these physique components which evince websites of elevated glucose metabolism. hence, a mixture of metabolic and morphologic tactics will increase tumor detection and alter the healing method. during this gentle, an atlas together with puppy, CT, MRI, and histology facts turns out fascinating to mix metabolic and morphologic imaging. This booklet offers an outline of the to be had facts which can be of serious curiosity not just for experts in radiology and nuclear medication, but in addition for oncologists.
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Extra resources for Atlas of Clinical PET in Oncology: PET versus CT and MRI
Patient and History: 44-year-old patient with a nasophar- ynx carcinoma (11/96); suspicion of a local recurrence with infiltration into the maxillary sinus (4/97); staging. Technique: Transmission-corrected scans with a slice thickness of 4 mm, image reconstruction by filtered backprojection. PET Results: The coronal (a) and transaxial (b) views of the thorax show one larger and a minor focus in projection on the middle part of the dorsal left lung, paravertebrally localized. Histology: Squamous cell carcinoma.
2 Distant metastases (AJCC Stage IV) AJCC stage IV includes advanced regional or distant metastases. Melanoma can metastasize to almost every organ and tissue. In clinical series, the most frequent metastatic sites are (in decreasing order) the skin and lymph nodes, lungs, liver, brain, and bone. In contrast, the frequencies detected in autopsy series are much higher, culminating in the lungs, followed by the liver, skin, brain, gastrointestinal tract and other visceral sites. Generally, patients with systemic metastases have very poor prognoses with a mean survival of about 6 months.
The patient had received chemotherapy 6 weeks prior to the PET study. Technique: Transmission-corrected scans with a slice thickness of 4 mm, image reconstruction by filtered backproj ection. PET Results: Coronal (a), transverse (b) and sagittal (c) PET views show a small focus with an intense FDG accumulation in the upper oral cavity. The FDG PET was able to reveal bilateral cervical lymph node involvement (not shown). The sagittal (c) view shows diffuse tracer accumulation in the sternum, spine and the stomach.
Atlas of Clinical PET in Oncology: PET versus CT and MRI by H.-J. Biersack (auth.), Hans Bender MD, Holger Palmedo MD, Hans-Jürgen Biersack MD, Peter E. Valk MD (eds.)